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CricKNOmics Magazine Volume 1 Issue 1 September2018
From the Editor
Team CricKNOmics is a
beginner in issuing a Science Magazine. The main aim of the team is to make
theoretical aspects into application dependent studies and explaining about new
technologies and development in Biotech sector. Being a lifescience graduate
and a researcher, the team has the core responsibility...
Cell Free Circulating DNA (cfDNA)
Cell free circulating DNA (cfDNA) are free floating, non-encapsulated DNA fragments that enter the bloodstream during apoptosis or necrosis. cfDNA are double stranded, fragmented approximately 150bp to 180 bp length. Many studies have suggested the potential utility of the cfDNA in prenatal diagnosis, early cancer detection and diagnosis of infectious...
Glycogen storage disease Type II – An Autosomal disorder
Introduction and History:
Autosomal diseases are inheriting a disease, condition or trait depending mainly on the affected chromosome. It may be either dominant or recessive. Some of the examples are – cystic fibrosis, sickle cell anaemia, Tay-Sachs disease etc. Several other conditions are also categorized under autosomal recessive metabolic diseases...
RNA interference – Evolution in nucleic acid therapy
Introduction
Evolution of Nucleic acid therapy has started or hypothesized in 1972. First and foremost technology evolved is the ‘Gene Therapy’ which was a breakthrough in treating several genetic disorders etc. The therapy involves the replacement of a mutated gene by a therapeutic gene as ‘a drug’ using specific delivery...
CRISPR - editing of gene therapy itself. . .!!
A decade ago, Zinc Finger Nuclease (ZFN), transcription activator-like effector nucleases
(TALENS) are the pioneers of gene editing tools. In recent times, CRISPR has
taken away the genome editing research into the next level.
CRISPR - Clustered Regularly
Interspaced Short Palindromic Repeat, is a repeated...
TOP 10 BIOWEAPONS OF THE WORLD
Bioweapon 10: Small pox
At the orders of Cmdr. Sir Jeffrey Amherst, British forces infamously distributed smallpox-infected blankets to Native American tribes in Ottawa. The native inhabitants of the Americas were particularly susceptible to the illness since, unlike their European invaders, they hadn't encountered...
